BDBM281089 US10022354, Example 29

SMILES CC(C)c1cc([nH]n1)C(=O)N1CC[C@H](C1)NC(=O)C1CC1

InChI Key InChIKey=CXEXTVGTDZRKJS-LLVKDONJSA-N

Data  18 IC50  1 Kd  1 EC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 281089   

TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM281089(US10022354, Example 29)
Affinity DataIC50:  56nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged KDM5B expressed in baculovirus infected Sf9 insect cells using H3K4me3 peptide as substrate af...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM281089(US10022354, Example 29)
Affinity DataIC50:  60nMAssay Description:Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM281089(US10022354, Example 29)
Affinity DataIC50:  56nMAssay Description:Inhibition of KDM5B (unknown origin ) by TR-FRET assayMore data for this Ligand-Target Pair